Tag Archives: top publications

Top 10 Cardiology Articles of the week

Top 10 Cardiology Articles of the week (17.11.14-23.11.14)

1. A Polypill Strategy to Improve Adherence:Results From the FOCUS Project
Compared with the 3 drugs given separately, the use of a polypill strategy met the                   primary endpoint for adherence for secondary prevention following an acute MI

2. Six-month versus 24-month dual antiplatelet therapy after implantation of drug eluting    stents in patients non-resistant to aspirin: ITALIC, a randomized multicenter trial 
The ITALIC trial showed that rates of bleeding and of thrombotic events were not significantly different according to 6- versus 24-month DAPT after PCI with new-generation DES in good aspirin responders.

3.  First-in-Man Transseptal Implantation of a “Surgical-Like” Mitral Valve Annuloplasty Device for Functional Mitral Regurgitation

4.  Pressure-Wire-Guided Percutaneous Transluminal Pulmonary Angioplasty

5.  AVOIDing Oxygen in Suspected STEMI Tied to Smaller Infarcts, Less Recurrent MI

6.  Percutaneous Left Atrial Appendage Closure vs Warfarin for Atrial Fibrillation. A Randomized Clinical Trial

7.  Meta-analysis Questions One-Size-Fits-All Anticoagulant Strategy in STEMI Patients

8.  Periprocedural Complications and Long-Term Outcome After Alcohol Septal Ablation Versus Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy

9.  Spontaneous Coronary Artery Dissection Revascularization Versus Conservative Therapy

10.  Surgical Treatment of Moderate Ischemic Mitral Regurgitation

Top 10 Cardiology articles of the week

Top 10 Cardiology articles of the week (10.11.14-16.11.14)

Hello friends , I have been busy for sometime. Now journal scan is back again after a brief interruption. I have chosen articles on general cardiology and interventional cardiology

1. The optimal management of anti-thrombotic therapy after valve replacement:                          certainties and uncertainties

2. Ivabradine in Stable Coronary Artery Disease without Clinical Heart Failure

3. The Unnatural History of Tetralogy of Fallot: Prospective Follow-Up of 40 Years After Surgical Correction

4. Clinical Outcomes and Improved Survival in Patients With Protein-Losing Enteropathy After the Fontan Operation

5. Immediate and midterm outcomes following primary PCI with bioresorbable vascular   scaffold implantation in patients with ST-segment myocardial
infarction: insights from the multicentre “Registro ABSORB Italiano” (RAI registry)

 

6. Second-Generation Drug-Eluting Stent Implantation Followed by 6- Versus 12-Month Dual Antiplatelet Therapy. The SECURITY Randomized Clinical Trial

7. Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI

 

8. The QT Interval Is Associated With Incident Cardiovascular Events

9. Endovascular Treatment of Mycotic Aortic Aneurysms: A European Multicenter Study

10.Intracoronary Delivery of Injectable Bioabsorbable Scaffold (IK-5001) to Treat Left Ventricular Remodeling After ST-Elevation Myocardial Infarction. A First-in-Man Study

PARADIGM-HF Trial

A new class of drug (Neprilysin inhibitor ) when combined with angiotensin receptor blocker , has been shown to be better than Enalapril.

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure — NEJM.

Top 10 Cardiology articles of the week (07.07.14-13.07.14)

1.Comprehensive Analysis of Mortality Among Patients Undergoing TAVR: Results of the PARTNER Trial
J Am Coll Cardiol. 2014;64(2):158-168

2. Glycosylated hemoglobin A1c as a marker predicting the severity of coronary artery disease and early outcome in patients with stable angina
Lipids Health Dis. 2014; 13: 89

3.Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes
JAMA. 2014;311(22):2288-2296

4.Association of Bariatric Surgery With Long-term Remission of Type 2 Diabetes and With Microvascular and Macrovascular Complications
JAMA. 2014;311(22):2297-2304

5.Prophylaxis against Venous Thromboembolism in Ambulatory Patients with Cancer

N Engl J Med 2014; 370:2515-2519

6.CardioDex: First human experience of thermal arterial closure

7. Minimizing femoral artery access complications during percutaneous coronary intervention: A comprehensive review

8.Complications related to transhepatic venous access in the catheterization laboratory—A single center 12-year experience of 124 procedures

9.Early outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy

10.Percutaneous Mitral Valve Repair for Mitral Regurgitation in High-Risk Patients Results of the EVEREST II Study
J Am Coll Cardiol. 2014;64(2):172-181

Top 10 Cardiology articles of the week (30.6.14- 6.7.14)

1. Prospective Randomized Evaluation of the Watchman Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Versus Long-Term Warfarin Therapy : The PREVAIL Trial.
In this trial, LAA occlusion was noninferior to warfarin for ischemic stroke                                      prevention or systemic embolism >7 days’ post-procedure. Although noninferiority                was not achieved for overall efficacy, event rates were low and numerically                                      comparable in both arms. Procedural safety has significantly improved. This trial provides additional data that LAA occlusion is a reasonable alternative to warfarin therapy for stroke prevention in patients with NVAF who do not have an absolute contraindication to short-term warfarin therapy.
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2.Stent Thrombosis in New-Generation Drug-Eluting Stents in Patients With STEMI Undergoing Primary PCI A Report From SCAAR.

Patients treated with n-DES (new generation DES)  have a lower risk of early/late ST  (stent thrombosis) than patients treated with BMS. The risk of very late ST  is low and comparable between n-DES and BMS up to 3 years of follow-up, whereas o-DES  (older generation DES) treatment is associated with an increased risk of very late ST. The current STEMI guidelines might require an update in light of the results of this and other recent studies.

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3.Clinical Outcomes and Improved Survival in Patients With Protein-Losing Enteropathy After the Fontan Operation.

http://content.onlinejacc.org/article.aspx?articleID=1886825
4.Hypertrophic Cardiomyopathy Present and Future, With Translation Into Contemporary Cardiovascular Medicine
http://content.onlinejacc.org/article.aspx?articleID=1886834

 
5.Dual antiplatelet therapy in patients with stable coronary artery disease in modern practice: Prevalence, correlates and impact on prognosis
(from the CORONOR study)
About one-quarter of patients with stable coronary artery disease (CAD) are prescribed dual antiplatelet therapy (DAPT), probably due to factors such as MI or revascularization within recent years, diffuse atherosclerosis, and DES implantation. Nonetheless, these patients are no more likely to be protected against future ischemic events than those receiving aspirin or clopidogrel alone.

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6.Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention:results from the phase II RADAR-PCI study.
High-level factor IXa inhibition in ACS patients undergoing PCI, with at least 50% reversal, has a favourable bleeding profile and appears effective at suppressing ischaemic events and thrombotic complications. Larger phase trials in PCI are warranted.
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7.Sitagliptin Use in Patients With Diabetes and Heart Failure: A Population-Based Retrospective Cohort Study.
There is considerable uncertainty about the safety of sitagliptin in patients with T2DM and HF, and current guidelines from the American Diabetes Association suggest caution with the use of antihyperglycemics in patients with HF. This study adds to the mounting evidence that DPP-4 inhibitors may increase the risk of HF, challenging a platform of basic science data that DPP-4 inhibition may actually have a beneficial impact on cardiovascular function.
Read more

 
8.Lifetime Prevalence of Congenital Heart Disease in the General Population from 2000 to 2010

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9.Insulin pump treatment compared with multiple daily injections for treatment of type 2 diabetes (OpT2mise): a randomised open-label controlled trial

 

 
10.Long-term Survival in Patients Undergoing Percutaneous Interventions With or Without Intracoronary Pressure Wire Guidance or Intracoronary Ultrasonographic Imaging: A Large Cohort Study
In this large observational study, FFR-guided PCI and IVUS-guided PCI were not associated with improved long-term survival compared with standard angiography-guided PCI. The use of FFR was associated with the implantation of fewer stents.
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Top 10 Cardiology articles of the week (23.6.14-29.6.14)

Top cardiology publications of the week

The below is given a list of top 10 cardiology articles which are clinically relevant and have a potential to influence practice

1. Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic         Heart Disease: A Consensus Statement From the American Heart Association

2. Efficacy and Safety of Rivaroxaban Compared with Warfarin among Elderly Patients with        Nonvalvular Atrial Fibrillation in the ROCKET AF Trial

3. Atrial Fibrillation in Patients with Cryptogenic Stroke

4. Cryptogenic Stroke and Underlying Atrial Fibrillation

5.  STARTS-2 Long-Term Survival With Oral Sildenafil Monotherapy in Treatment-Naive                    Pediatric Pulmonary Arterial Hypertension

6.  Haemodynamic-guided fluid administration for the prevention of contrast-induced                 acute kidney injury: the POSEIDON randomised controlled trial

7. Effect of Evolocumab or Ezetimibe Added to Moderate- or High-Intensity Statin Therapy        on LDL-C Lowering in Patients With Hypercholesterolemia The LAPLACE-2 Randomized          Clinical Trial

8. Prognostic Value of Echocardiography in Normotensive Patients With Acute Pulmonary          Embolism

9.  First human experience of thermal arterial closure

10.  Clinical Profile and Prognostic Value of Anemia at the Time of Admission and                                Discharge Among Patients Hospitalized for Heart Failure With Reduced Ejection                           Fraction Findings From the EVEREST Trial