Deﬁnition of myocardial infarction Criteria for acute myocardial infarction : The term acute myocardial infarction (MI) should be used when there is evidence of myocardial necrosis in a clinical setting consistent with acute myocardial ischaemia. Under these conditions any one of the following criteria meets the diagnosis for MI: • Detection of a rise and/or […]
Top 10 Cardiology Articles of the week (24.11.14 – 30.11.14) 1. Transcatheter Closure of Large Atrial Septal Defects: Feasibility and Safety in a Large Adult and Pediatric Population Conclusions—Closure of large atrial septal defects using the Amplatzer device is safe and effective in both adults and children. Superior and posterior rim deficiencies are associated with […]
Meta-analysis Confirms Benefits of FFR-Guided Revascularization – Journal News – TCTMD.
HPS2-THRIVE trial Among patients with atherosclerotic vascular disease, the addition of extended-release niacin–laropiprant to statin-based LDL cholesterol–lowering therapy did not significantly reduce the risk of major vascular events but did increase the risk of serious adverse events. Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients — NEJM.
What is sudden cardiac death (SCD) ? Sudden cardiac death is defined as natural death from cardiac causes, heralded by abrupt loss of consciousness within 1 hour of the onset of an acute change in cardiovascular status. Related terms are sudden cardiac arrest and cardiovascular collapse. Sudden cardiac arrest means abrupt cessation of cardiac mechanical […]
Loss-of-function mutations in APOC3 were associated with low levels of triglycerides and a reduced risk of ischemic cardiovascular disease Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease — NEJM.
Percutaneous ventricular restoration therapy This is a new form of device therapy for heart failure. The device used is Parachute implant® (http://www.cardiokinetix.com/). Parachute implant is an umbrella shaped device that is inserted into the left ventricle. Pathophysiological basis of use: – In post MI patients there is progressive LV remodelling (progressive dilatation of the […]
STENTYS SELF APPOSITION SES: It is a self-expandable sirolimus-eluting coronary stent system, similar in concept to other self-expanding systems. Watch the video: Stentys self-apposition SES APPOSITION IV trial: –Patients – 152 patients presenting with STEMI. –Design: Patients were randomized to Stentys self-apposing SES (Stentys, Paris, France; n = 90) vs Resolute zotarolimus-eluting stent (ZES; Medtronic, […]
Coronary artery disease The heart like any other organ in the body needs constant supply of blood to survive. Blood reaches different parts of the heart through the coronary arteries. Coronary arteries are of vital importance for the sustenance of life. The different normal functions of the coronary arteries include: 1. Carrying blood to different […]
CardioSource – FDA Approves Vorapaxar to Reduce Heart Attack and Stroke Risks in HighRisk Patients. The U.S. Food and Drug Administration (FDA) has approved vorapaxar (Zontivity) to reduce the risk for MI, stroke, cardiovascular-related death and coronary revascularization among patients who have previously experienced MI or peripheral artery disease. Vorapaxar is the first in a […]