Antiplatelet Therapy for Stable CAD in AF Patients Taking an Oral Anticoagulant

Background—The optimal long-term antithrombotic treatment of patients with coexisting atrial fibrillation and stable coronary artery disease is unresolved, and commonly, a single antiplatelet agent is added to oral anticoagulation. The study investigated the effectiveness and safety of adding antiplatelet therapy to vitamin K antagonist (VKA) in atrial fibrillation patients with stable coronary artery disease. Methods […]

MI rates with Ticagrelor (from PLATO)

This article in JACC examines the rates of MI in patients with ACS treated with ticagrelor vs clopidogrel. The rates of overall MI at 12 months: 1. Ticagrelor- 5.8% 2. Clopidogrel – 6.9% 3. Nonprocedural MI (HR: 0.86; 95% CI: 0.74 to 1.01) and MI related to percutaneous      coronary intervention or stent thrombosis tended […]

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